Yayin da fata ke tsufa, akwai raguwar aikin jiki. Waɗannan canje-canjen suna faruwa ne ta hanyar abubuwan da ke haifar da tsufa (na yau da kullun) da kuma na waje (wanda galibi ke haifar da UV). Masana kimiyyar tsirrai suna ba da fa'idodi masu yuwuwa don yaƙar wasu daga cikin alamun tsufa. A nan, muna duba wasu nau'ikan tsirrai da shaidar kimiyya da ke bayan ikirarinsu na hana tsufa. Masana kimiyyar tsirrai na iya ba da maganin kumburi, maganin hana tsufa, danshi, kariya daga UV, da sauran tasirin. An lissafa nau'ikan tsirrai da yawa a matsayin sinadaran da ke cikin shahararrun kayan kwalliya da kayan kwalliya, amma kaɗan ne kawai aka tattauna a nan. An zaɓi waɗannan ne bisa ga samuwar bayanan kimiyya, sha'awar marubutan, da kuma yadda ake ganin "shaharar" samfuran kwalliya da na kwalliya na yanzu. Abubuwan da aka yi bita a nan sun haɗa da man argan, man kwakwa, crocin, feverfew, shayin kore, marigold, rumman, da waken soya.
Kalmomi masu mahimmanci: ganyen botanical; hana tsufa; man argan; man kwakwa; crocin; feverfew; shayin kore; marigold; rumman; waken soya
3.1. Man Argan
3.1.1. Tarihi, Amfani, da Da'awa
Man argan yana da matuƙar amfani a ƙasar Maroko kuma ana samunsa ne daga irin Argania sponosa L. Yana da amfani da yawa na gargajiya kamar girki, magance cututtukan fata, da kula da fata da gashi.
3.1.2. Tsarin Aiki da Tsarin Aiki
Man argan ya ƙunshi kashi 80% na kitse mai monounsaturated da kashi 20% na kitse mai cikakken kitse kuma ya ƙunshi polyphenols, tocopherols, sterols, squalene, da triterpene alcohol.
3.1.3. Shaidar Kimiyya
A al'adance ana amfani da man argan a Maroko don rage launin fuska, amma ba a fahimci tushen kimiyya na wannan da'awar ba a da. A wani bincike da aka yi kan beraye, man argan ya hana bayyanar tyrosinase da dopachrome tautomerase a cikin ƙwayoyin melanoma na murine B16, wanda ya haifar da raguwar adadin melanin da ya dogara da kashi. Wannan yana nuna cewa man argan na iya zama mai hana ƙwayoyin melanin, amma ana buƙatar gwaje-gwajen sarrafawa na bazuwar (RTC) a cikin mutane don tabbatar da wannan hasashe.
Wani ƙaramin RTC na mata 60 bayan daina al'ada ya nuna cewa shan man argan a kullum da/ko shafa a jiki ya rage asarar ruwan transepidermal (TEWL), inganta sassaucin fata, bisa ga ƙaruwar R2 (ƙarfin fata), R5 (ƙarfin fata mai ƙarfi), da kuma R7 (ƙarfin halitta) sigogi da raguwar lokacin aiki na resonance (RRT) (ma'auni da ya shafi sassaucin fata). An yi wa ƙungiyoyin bazuwar don shan man zaitun ko man argan. Dukansu ƙungiyoyin sun shafa man argan a wuyan hannu na hagu kawai. An ɗauki ma'auni daga wuyan hannu na dama da hagu. An ga ci gaba a sassauci a cikin ƙungiyoyin biyu a wuyan hannu inda aka shafa man argan a saman jiki, amma a wuyan hannu inda ba a shafa man argan ba kawai ƙungiyar da ke shan man argan tana da ƙaruwa mai yawa a sassauci [31]. An danganta wannan da ƙaruwar sinadarin antioxidant a cikin man argan idan aka kwatanta da man zaitun. Ana hasashen cewa wannan na iya faruwa ne saboda yawan sinadarin Vitamin E da ferulic acid, waɗanda aka sani da antioxidants.
3.2. Man Kwakwa
3.2.1. Tarihi, Amfani, da Da'awa
Ana samun man kwakwa ne daga busasshen 'ya'yan itacen Cocos nucifera kuma yana da amfani da yawa, na tarihi da na zamani. An yi amfani da shi azaman turare, maganin fata, da gyaran gashi, da kuma a cikin kayayyakin kwalliya da yawa. Duk da cewa man kwakwa yana da abubuwa da yawa da aka samo daga gare shi, ciki har da acid na kwakwa, acid na kwakwa mai hydrogenated, da man kwakwa mai hydrogenated, za mu tattauna da'awar bincike da ke da alaƙa da man kwakwa mai budurwa (VCO), wanda ake shirya shi ba tare da zafi ba.
An yi amfani da man kwakwa don sanyaya fatar jarirai kuma yana iya zama da amfani wajen magance cututtukan atopic dermatitis saboda kaddarorinsa na danshi da kuma tasirinsa ga Staphylococcus aureus da sauran ƙwayoyin cuta na fata a cikin marasa lafiya da ke da cutar atopic. An nuna cewa man kwakwa yana rage yawan shigar S. aureus a fatar manya da ke da cutar atopic dermatitis a cikin RTC mai makanta biyu.
3.2.2. Tsarin Aiki da Tsarin Aiki
Man kwakwa ya ƙunshi kashi 90-95% na sinadarin triglycerides mai cikakken ƙarfi (lauric acid, myristic acid, caprylic acid, capric acid, da palmitic acid). Wannan ya bambanta da yawancin man kayan lambu/'ya'yan itace, waɗanda galibi suna ƙunshe da kitse mara cikakken ƙarfi. Man triglycerides masu cikakken ƙarfi da aka shafa a jiki suna aiki don sanya fata ta jike ta hanyar daidaita gefuna na corneocytes masu bushewa da kuma cike gibin da ke tsakaninsu.
3.2.3. Shaidar Kimiyya
Man kwakwa na iya sanya fata ta tsufa ta yi laushi. Kashi sittin da biyu cikin ɗari na fatty acids da ke cikin VCO suna da tsayi iri ɗaya kuma kashi 92 cikin ɗari suna da cikakken kitse, wanda ke ba da damar matsewa mai ƙarfi wanda ke haifar da tasirin rufewa fiye da man zaitun. Ana raba triglycerides da ke cikin man kwakwa ta hanyar lipases a cikin fata na yau da kullun zuwa glycerin da fatty acids. Glycerin wani abu ne mai ƙarfi na humectant, wanda ke jawo ruwa zuwa layin corneal na epidermis daga muhallin waje da kuma zurfin yadudduka na fata. Fatty acids da ke cikin VCO suna da ƙarancin sinadarin linoleic acid, wanda ya dace tunda linoleic acid na iya haifar da haushi ga fata. Man kwakwa ya fi man ma'adinai kyau wajen rage TEWL a cikin marasa lafiya da ke fama da atopic dermatitis kuma yana da tasiri da aminci kamar man ma'adinai wajen magance xerosis.
Lauric acid, wanda shine tushen monolaurin kuma muhimmin sashi na VCO, yana iya samun kaddarorin hana kumburi, yana iya daidaita yaduwar ƙwayoyin rigakafi kuma yana da alhakin wasu tasirin maganin rigakafi na VCO. VCO yana ɗauke da babban adadin ferulic acid da p-coumaric acid (duka phenolic acid), kuma babban matakan waɗannan phenolic acid suna da alaƙa da ƙaruwar ƙarfin antioxidant. Phenolic acid suna da tasiri akan lalacewar da UV ke haifarwa. Duk da haka, duk da ikirarin cewa man kwakwa na iya aiki azaman kariya daga hasken rana, nazarin in vitro ya nuna cewa yana ba da damar toshe UV kaɗan ko babu.
Baya ga tasirin da yake da shi na danshi da kuma maganin hana tsufa, samfuran dabbobi sun nuna cewa VCO na iya rage lokacin warkar da rauni. An sami ƙaruwar matakin collagen mai narkewa na pepsin (haɗin gwiwa mai yawa na collagen) a cikin raunukan da aka yi wa magani da VCO idan aka kwatanta da waɗanda aka sarrafa. Binciken histopathology ya nuna ƙaruwar yaduwar fibroblast da neovascularization a cikin waɗannan raunuka. Ana buƙatar ƙarin bincike don ganin ko shafa VCO a saman fata na iya ƙara yawan collagen a cikin fatar ɗan adam da ta tsufa.
3.3. Crocin
3.3.1. Tarihi, Amfani, Da'awa
Crocin wani sinadari ne mai aiki a fannin ilmin halitta na saffron, wanda aka samo daga busasshen ƙwayar Crocus sativus L. Ana noma Saffron a ƙasashe da yawa ciki har da Iran, Indiya, da Girka, kuma ana amfani da shi a magungunan gargajiya don rage cututtuka iri-iri, ciki har da baƙin ciki, kumburi, cututtukan hanta, da sauransu.
3.3.2. Tsarin Aiki da Tsarin Aiki
Crocin ne ke da alhakin launin saffron. Haka kuma ana samun Crocin a cikin 'ya'yan itacen Gardenia jasminoides Ellis. An rarraba shi a matsayin carotenoid glycoside.
3.3.3. Shaidar Kimiyya
Crocin yana da tasirin antioxidant, yana kare squalene daga peroxidation da UV ke haifarwa, kuma yana hana sakin masu shiga tsakani na kumburi. An nuna tasirin antioxidant a cikin gwaje-gwajen in vitro wanda ya nuna ingantaccen aikin antioxidant idan aka kwatanta da Vitamin C. Bugu da ƙari, crocin yana hana peroxidation na membrane na tantanin halitta da UVA ke haifarwa kuma yana hana bayyanar masu shiga tsakani da yawa waɗanda suka haɗa da IL-8, PGE-2, IL-6, TNF-α, IL-1α, da LTB4. Hakanan yana rage bayyanar kwayoyin halitta da yawa waɗanda suka dogara da NF-κB. A cikin wani bincike da aka yi amfani da fibroblasts na ɗan adam, crocin ya rage ROS da UV ke haifarwa, ya haɓaka bayyanar furotin na matrix na extracellular Col-1, kuma ya rage adadin ƙwayoyin halitta masu tasowa bayan radiation UV. Yana rage samar da ROS kuma yana iyakance apoptosis. An nuna Crocin yana danne hanyoyin siginar ERK/MAPK/NF-κB/STAT a cikin ƙwayoyin HaCaT a cikin vitro. Kodayake crocin yana da yuwuwar a matsayin maganin tsufa na cosmeceutical, mahaɗin yana da rauni. An yi bincike kan amfani da nanostructured lipid dispersions don amfani da shi a jiki tare da sakamako mai kyau. Domin tantance tasirin crocin a cikin jiki, ana buƙatar ƙarin samfuran dabbobi da gwaje-gwajen asibiti na bazuwar.
3.4. Zazzabi
3.4.1. Tarihi, Amfani, Da'awa
Feverfew, Tanacetum parthenium, wata ganye ce da ake amfani da ita a magungunan gargajiya domin dalilai daban-daban.
3.4.2. Tsarin Aiki da Tsarin Aiki
Feverfew yana ɗauke da parthenolide, wani sesquiterpene lactone, wanda zai iya zama sanadin wasu daga cikin tasirinsa na hana kumburi, ta hanyar hana NF-κB. Wannan hana NF-κB da alama ba ya dogara da tasirin antioxidant na parthenolide. Parthenolide ya kuma nuna tasirin maganin ciwon daji akan cutar kansar fata da UVB ke haifarwa da kuma akan ƙwayoyin melanoma a cikin vitro. Abin takaici, parthenolide na iya haifar da halayen rashin lafiyan, ƙuraje a baki, da kuma dermatitis na rashin lafiyan. Saboda waɗannan damuwa, yanzu gabaɗaya ana cire shi kafin a ƙara feverfew a cikin samfuran kwalliya.
3.4.3. Shaidar Kimiyya
Saboda yuwuwar rikitarwa da amfani da parthenolide a jiki, wasu samfuran kwalliya na yanzu da ke ɗauke da feverfew suna amfani da parthenolide-depleted feverfew (PD-feverfew), wanda ke da'awar cewa ba shi da yuwuwar jin zafi. PD-feverfew na iya haɓaka aikin gyaran DNA na ciki a cikin fata, wanda hakan zai iya rage lalacewar DNA da UV ke haifarwa. A cikin wani bincike a cikin vitro, PD-feverfew ya rage samuwar hydrogen peroxide da UV ke haifarwa da kuma rage sakin cytokine mai kumburi. Ya nuna tasirin antioxidant mafi ƙarfi fiye da mai kwatantawa, Vitamin C, da raguwar erythema da UV ke haifarwa a cikin RTC mai batutuwa 12.
3.5. Shayin Kore
3.5.1. Tarihi, Amfani, Da'awa
An sha shayin kore don amfanin lafiyarsa a China tsawon ƙarni da yawa. Saboda tasirinsa mai ƙarfi na hana tsufa, akwai sha'awar haɓaka wani tsari mai ƙarfi wanda ake iya samu daga jiki.
3.5.2. Tsarin Aiki da Tsarin Aiki
Shayin kore, daga Camellia sinensis, ya ƙunshi mahadi masu aiki da yawa waɗanda ke da tasirin hana tsufa, gami da maganin kafeyin, bitamin, da polyphenols. Manyan polyphenols a cikin shayin kore sune catechins, musamman gallocatechin, epigallocatechin (ECG), da epigallocatechin-3-gallate (EGCG). Epigallocatechin-3-gallate yana da kaddarorin antioxidant, kariya daga hasken rana, immunomodulatory, anti-angiogenic, da anti-inflammatory. Shayin kore kuma yana ɗauke da adadi mai yawa na flavonol glycoside kaempferol, wanda ke sha sosai a cikin fata bayan an shafa shi a jiki.
3.5.3. Shaidar Kimiyya
Cirewar shayin kore yana rage samar da ROS a cikin jiki a cikin vitro kuma yana rage necrosis da ROS ke haifarwa. Epigallocatechin-3-gallate (wani shayin kore polyphenol) yana hana fitar hydrogen peroxide da UV ke haifarwa, yana hana phosphorylation na MAPK, kuma yana rage kumburi ta hanyar kunna NF-κB. Ta amfani da fatar ex vivo daga mace mai lafiya 'yar shekara 31, an yi wa fatar da aka yi wa fenti da farin ko kore, wanda aka riga aka yi wa fatar da aka yi wa fenti da ruwan shayi mai launin fari ko kore ya nuna riƙewar ƙwayoyin Langerhans (ƙwayoyin da ke gabatar da antigen waɗanda ke da alhakin haifar da rigakafi a cikin fata) bayan fallasa hasken UV.
A cikin samfurin beraye, shafa ruwan shayin kore a jiki kafin a fallasa shi ga hasken UV ya haifar da raguwar erythema, raguwar shigar ƙwayoyin leukocytes a fata, da kuma raguwar aikin myeloperoxidase. Hakanan yana iya hana 5-α-reductase.
Nazarce-nazarce da dama da suka shafi mutane sun tantance fa'idodin da ke tattare da amfani da shayin kore a jiki. Shafa shayin kore a jiki ta hanyar shafawa ... A wani bincike daban, an rarraba manyan masu aikin sa kai 90 zuwa ƙungiyoyi uku: Ba a yi magani ba, shayin kore a jiki, ko shayin farin a jiki. An ƙara raba kowace ƙungiya zuwa matakai daban-daban na hasken UV. An gano cewa abin da ke kare rana a jiki shine kusan SPF 1.
3.6. Marigold
3.6.1. Tarihi, Amfani, Da'awa
Marigold, Calendula officinalis, shuka ce mai ƙamshi mai yuwuwar warkarwa. An yi amfani da ita a magungunan gargajiya a Turai da Amurka a matsayin maganin shafawa don ƙonewa, raunuka, raunuka, da kuraje. Marigold ya kuma nuna tasirin maganin ciwon daji a cikin samfuran fata na cutar kansar fata wadda ba ta shafi melanoma.
3.6.2. Tsarin Aiki da Tsarin Aiki
Manyan sinadaran da ke cikin marigolds sune steroids, terpenoids, free and esterified triterpene alcohols, phenolic acid, flavonoids, da sauran mahadi. Duk da cewa wani bincike ya nuna cewa amfani da ruwan marigold a saman jiki na iya rage tsananin da radadin radiation dermatitis a cikin marasa lafiya da ke karɓar radiation don ciwon nono, wasu gwaje-gwajen asibiti ba su nuna wani fifiko ba idan aka kwatanta da amfani da man shafawa mai ruwa-ruwa kawai.
3.6.3. Shaidar Kimiyya
Marigold yana da ƙarfin antioxidant da tasirin cytotoxic akan ƙwayoyin cutar kansa na ɗan adam a cikin samfurin ƙwayoyin fata na ɗan adam na in vitro. A cikin wani bincike daban na in vitro, an kimanta wani kirim mai ɗauke da man calendula ta hanyar amfani da UV spectrophotometric kuma an gano yana da tasirin sha a cikin kewayon 290-320 nm; an ɗauka cewa wannan yana nufin cewa amfani da wannan kirim ɗin yana ba da kyakkyawan kariya daga rana. Duk da haka, yana da mahimmanci a lura cewa wannan ba gwajin in vivo bane wanda ya ƙididdige mafi ƙarancin adadin erythema a cikin masu sa kai na ɗan adam kuma har yanzu ba a san yadda wannan zai fassara ba a cikin gwaje-gwajen asibiti.
A cikin wani samfurin in vivo murine, ruwan marigold ya nuna ƙarfin tasirin antioxidant bayan fallasa UV. A wani bincike daban, wanda ya shafi berayen albino, amfani da man calendula mai mahimmanci a jiki ya rage malondialdehyde (alamar damuwa ta oxidative) yayin da yake ƙara matakan catalase, glutathione, superoxide dismutase, da ascorbic acid a cikin fata.
A wani bincike da aka yi na tsawon makonni takwas wanda aka yi wa mutane 21 da suka makance, shafa man calendula a kunci ya kara tauri amma bai yi wani tasiri mai mahimmanci kan laushin fata ba.
Wani abin da zai iya hana amfani da marigold a cikin kayan kwalliya shi ne cewa marigold sananne ne wanda ke haifar da rashin lafiyar fata, kamar sauran membobin dangin Compositae.
3.7. Rumman
3.7.1. Tarihi, Amfani, Da'awa
Rumman, Punica granatum, yana da ƙarfin hana tsufa kuma an yi amfani da shi a cikin samfura da yawa a matsayin maganin hana tsufa. Babban sinadarin hana tsufa yana sa ya zama sinadari mai ban sha'awa a cikin kayan kwalliya.
3.7.2. Tsarin Aiki da Tsarin Aiki
Sinadaran da ke aiki a jikin rumman sune tannins, anthocyanins, ascorbic acid, niacin, potassium, da kuma piperidine alkaloids. Ana iya cire waɗannan sinadaran da ke aiki a jikin rumman daga ruwan 'ya'yan itace, tsaba, bawon, haushi, saiwoyi, ko kuma tushen rumman. Ana tsammanin wasu daga cikin waɗannan sinadaran suna da tasirin hana ƙari, hana kumburi, hana ƙwayoyin cuta, hana tsufa, da kuma kariya daga hasken rana. Bugu da ƙari, rumman tushen polyphenols ne mai ƙarfi. Ellegic acid, wani ɓangare na ruwan 'ya'yan rumman, na iya rage launin fata. Saboda kasancewarsa sinadari mai kyau na hana tsufa, bincike da yawa sun binciki hanyoyin da za a ƙara shigar fata cikin wannan sinadari don amfani a jiki.
3.7.3. Shaidar Kimiyya
Cirewar 'ya'yan itacen rumman yana kare ƙwayoyin fibroblasts na ɗan adam, a cikin vitro, daga mutuwar ƙwayoyin halitta da UV ke haifarwa; wataƙila saboda raguwar kunna NF-κB, raguwar tsarin proapoptotic caspace-3, da kuma ƙaruwar gyaran DNA. Yana nuna tasirin hana ƙari a fata a cikin vitro kuma yana hana daidaita hanyoyin NF-κB da MAPK da UVB ke haifarwa. Shafawar haƙarƙarin rumman a jiki yana rage COX-2 a cikin fatar alade da aka fitar sabo, wanda ke haifar da tasirin hana kumburi mai yawa. Kodayake galibi ana ɗaukar cewa acid mai guba shine mafi yawan abubuwan da ke cikin cirewar rumman, wani samfurin murine ya nuna mafi girman aikin hana kumburi tare da daidaitaccen cirewar haƙarƙarin rumman idan aka kwatanta da acid mai guba kawai. Shafawar microemulsion na cirewar rumman ta amfani da polysorbate surfactant (Tween 80®) a cikin kwatancen fuska na makonni 12 da mutane 11, ya nuna raguwar melanin (saboda hana tyrosinase) da raguwar erythema idan aka kwatanta da sarrafa abin hawa.
3.8. Waken Soya
3.8.1. Tarihi, Amfani, Da'awa
Waken soya abinci ne mai yawan furotin wanda ke da sinadarai masu aiki waɗanda ke iya hana tsufa. Musamman ma, waken soya yana da yawan isoflavones, wanda zai iya haifar da tasirin hana ciwon daji da kuma tasirin estrogen saboda tsarin diphenolic. Waɗannan tasirin estrogen na iya yaƙi da wasu tasirin daina al'ada ga tsufan fata.
3.8.2. Tsarin Aiki da Tsarin Aiki
Waken soya, daga Glycine maxi, yana da yawan furotin kuma yana ɗauke da isoflavones, waɗanda suka haɗa da glycitein, equol, daidzein, da genistein. Waɗannan isoflavones, waɗanda kuma ake kira phytoestrogens, na iya samun tasirin estrogen a jikin ɗan adam.
3.8.3. Shaidar Kimiyya
Waken soya yana ɗauke da isoflavones da yawa waɗanda ke da yuwuwar hana tsufa. Daga cikin sauran tasirin halittu, glycitein yana nuna tasirin antioxidant. Fibroblasts na fata da aka yi wa magani da glycitein sun nuna ƙaruwar yaduwar ƙwayoyin halitta da ƙaura, ƙaruwar haɗakar nau'ikan collagen I da III, da raguwar MMP-1. A wani bincike daban, an haɗa ruwan waken soya da ruwan haematococcus (algae mai ruwan sabo kuma yana da yawan antioxidants), wanda ya rage yawan bayyanar MMP-1 mRNA da furotin. Daidzein, isoflavone na soya, ya nuna tasirin hana wrinkles, walƙiya fata, da kuma sanya fata ruwa. Diadzein na iya aiki ta hanyar kunna estrogen-receptor-β a cikin fata, wanda ke haifar da haɓaka bayyanar antioxidants na ciki da raguwar bayyanar abubuwan da ke haifar da yaduwar keratinocyte da ƙaura. Daidaiton isoflavonoid da aka samo daga soya ya ƙara yawan collagen da elastin da raguwar MMPs a cikin al'adar ƙwayoyin halitta.
Ƙarin nazarin murine a cikin jiki sun nuna raguwar mutuwar ƙwayoyin halitta da UVB ke haifarwa da kuma raguwar kauri a cikin ƙwayoyin halitta bayan an shafa ruwan isoflavone a jiki. A cikin wani bincike na gwaji da aka yi wa mata 30 bayan daina al'ada, shan ruwan isoflavone ta baki na tsawon watanni shida ya haifar da ƙaruwar kauri a cikin fata da kuma ƙaruwar collagen ta fata kamar yadda aka auna ta hanyar biopsy na fata a wuraren da rana ke kare su. A wani bincike daban, isoflavones na soya da aka tsarkake sun hana mutuwar keratinocyte da UV ke haifarwa da kuma raguwar TEWL, kauri a cikin fata, da kuma erythema a cikin fatar beraye da UV ke fallasa.
An yi gwajin RCT mai makanta biyu na mata 30 masu shekaru 45-55 da aka yi amfani da shi wajen tantance yanayin fata na tsawon makonni 24. Duk da cewa ƙungiyar da ta shafa estrogen a fata ta sami sakamako mai kyau, ƙungiyoyin biyu sun nuna ƙaruwar sinadarin collagen na fuska na nau'in I da III bisa ga biopsy na fata na preauricular. Soy oligopeptides na iya rage ma'aunin erythema a cikin fatar da UVB ta fallasa (hannun hannu) da kuma rage ƙwayoyin da ke ƙonewa da rana da kuma dimers na cyclobutene pyrimidine a cikin ƙwayoyin fata na UVB da aka yi amfani da su wajen haskaka fata. Wani gwaji na asibiti na makonni 12 wanda aka sarrafa ta hanyar makanta biyu a cikin abin hawa wanda ya shafi mata 65 waɗanda ke da matsakaicin lalacewar fuska ya nuna ci gaba a cikin launin fata mai laushi, ɓacin rai, rashin laushi, layuka masu laushi, laushin fata, da launin fata idan aka kwatanta da abin hawa. Tare, waɗannan abubuwan na iya bayar da yuwuwar tasirin hana tsufa, amma ana buƙatar ƙarin gwaje-gwaje na asibiti don nuna fa'idarsa yadda ya kamata.
4. Tattaunawa
Kayayyakin tsirrai, gami da waɗanda aka tattauna a nan, suna da yuwuwar tasirin hana tsufa. Hanyoyin da ake amfani da su wajen magance tsufa sun haɗa da ikon kawar da ƙwayoyin cuta masu guba waɗanda aka shafa a saman fata, ƙara kariya daga rana, ƙara danshi a fata, da kuma illoli da yawa da ke haifar da ƙaruwar samuwar collagen ko raguwar rushewar collagen. Wasu daga cikin waɗannan illolin ba su da yawa idan aka kwatanta da magunguna, amma wannan bai rage fa'idar da za su iya samu ba idan aka yi amfani da su tare da wasu matakai kamar guje wa rana, amfani da man shafawa na rana, danshi a kowace rana da kuma kulawar kwararrun likitoci kan yanayin fata da ke akwai.
Bugu da ƙari, ƙwayoyin halittar dabbobi suna ba da madadin sinadaran da ke aiki a fannin halitta ga marasa lafiya waɗanda suka fi son amfani da sinadaran "na halitta" kawai a fatarsu. Duk da cewa ana samun waɗannan sinadaran a cikin yanayi, yana da mahimmanci a jaddada wa marasa lafiya cewa wannan ba yana nufin cewa waɗannan sinadaran ba su da wani mummunan tasiri ba, a gaskiya ma, an san cewa samfuran tsire-tsire da yawa suna iya haifar da rashin lafiyar dermatitis.
Ganin cewa kayayyakin kwalliya ba sa buƙatar irin wannan shaidar don tabbatar da inganci, sau da yawa yana da wuya a tantance ko ikirarin tasirin hana tsufa gaskiya ne. Duk da haka, da yawa daga cikin magungunan tsirrai da aka lissafa a nan suna da tasirin hana tsufa, amma ana buƙatar ƙarin gwaje-gwaje na asibiti. Kodayake yana da wuya a annabta yadda waɗannan magungunan tsirrai za su amfanar da marasa lafiya da masu amfani kai tsaye a nan gaba, yana da yuwuwar cewa ga yawancin waɗannan magungunan tsirrai, za a ci gaba da gabatar da su azaman sinadaran a matsayin samfuran kula da fata kuma idan sun kiyaye fa'ida mai yawa, karɓuwa ga masu amfani, da kuma araha mafi kyau, za su ci gaba da kasancewa wani ɓangare na ayyukan kula da fata na yau da kullun, suna ba da ƙarancin fa'idodi ga lafiyar fata. Duk da haka, ga ƙayyadadden adadin waɗannan magungunan tsirrai, ana iya samun babban tasiri ga jama'a ta hanyar ƙarfafa shaidar tasirinsu na halitta, ta hanyar gwaje-gwajen biomarker na yau da kullun masu yawa sannan daga baya a gabatar da mafi kyawun manufofin ga gwajin asibiti.
Lokacin Saƙo: Mayu-11-2023
