Catharanthus Roseus Cire Foda
Catharanthus roseus cire fodawani foda ne na tsantsa wanda aka samo daga shukar Catharanthus roseus, wanda kuma aka sani da Madagascar periwinkle ko rosy periwinkle. Wannan shuka an san shi da kaddarorin magani kuma yana ƙunshe da mahaɗan bioactive iri-iri, gami da alkaloids irin su vinblastine da vincristine, waɗanda aka yi nazari don yuwuwar rigakafin cutar kansa.
Ana samun tsantsa foda yawanci ta hanyar fitar da mahaɗan bioactive daga kayan shuka sannan a sarrafa su zuwa foda don aikace-aikace daban-daban. Ana iya amfani da shi a cikin magungunan gargajiya, magunguna, ko saitunan bincike saboda yuwuwar kayan magani.
Catharanthus roseus sananne ne da kasancewa tsire-tsire na magani na almara saboda yana ɗauke da antitumor terpenoid indole alkaloids (TIAs), vinblastine da vincristine. A cikin maganin gargajiya na kasar Sin, an yi amfani da kayan da aka samu daga shukar don magance cututtuka kamar zazzabin cizon sauro, ciwon sukari, da lymphoma na Hodgkin. A cikin 1950s, vinca alkaloids an keɓe su daga Catharanthus roseus yayin da ake yin gwajin magungunan rigakafin ciwon sukari.
Catharanthus roseus, wanda aka fi sani da sunaidanu masu haske, Cape periwinkle, shukar kabari, Madagascar periwinkle, tsohuwar baiwa, ruwan hoda periwinkle, orfure periwinkle, wani nau'in tsire-tsire ne na shekara-shekara a cikin dangin Apocynaceae. Yana da ɗan ƙasa kuma yana da girma zuwa Madagascar amma ana girma a wani wuri a matsayin tsire-tsire na ado da magani, kuma yanzu yana da rarrabawar yanayi. Ita ce tushen magungunan vincristine da vinblastine, ana amfani da su don magance ciwon daji. An riga an haɗa shi a cikin jinsin Vinca kamar yaddaVinca rosea. Tana da sunaye da yawa daga cikin su akwai arivotaombelona ko rivotambelona, tonga, tongatse ko trongatse, tsimatiririnina, da vonenina.
| Babban Sinadaran Masu Aiki cikin Sinanci | Sunan Turanci | CAS No. | Nauyin Kwayoyin Halitta | Tsarin kwayoyin halitta |
| 长春胺 | Vincamine | 1617-90-9 | 354.44 | Saukewa: C21H26N2O3 |
| 脱水长春碱 | Anhydrovinblastine | 38390-45-3 | 792.96 | Saukewa: C46H56N4O8 |
| 異長春花苷內酰胺 | Strictosamide | 23141-25-5 | 498.53 | Saukewa: C26H30N2O8 |
| 四氢鸭脚木碱 | Tetrahydroalstonine | 6474-90-4 | 352.43 | Saukewa: C21H24N2O3 |
| 酒石酸长春瑞滨 | Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | Vinorelbine | 71486-22-1 | 778.93 | Saukewa: C45H54N4O8 |
| 长春新碱 | Vincristine | 57-22-7 | 824.96 | Saukewa: C46H56N4O10 |
| 硫酸长春新碱 | Vincristine sulfate | 2068-78-2 | 923.04 | Saukewa: C46H58N4O14S |
| 硫酸长春质碱 | Catharanthine sulfate | 70674-90-7 | 434.51 | Saukewa: C21H26N2O6S |
| 酒石酸长春质碱 | Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | Vinblastine | 865-21-4 | 810.99 | Saukewa: C46H58N4O9 |
| 长春质碱 | Catharanthine | 2468-21-5 | 336.43 | Saukewa: C21H24N2O2 |
| 文朵灵 | Vindoline | 2182-14-1 | 456.53 | Saukewa: C25H32N2O6 |
| 硫酸长春碱 | Vinblastine sulfate | 143-67-9 | 909.05 | Saukewa: C46H60N4O13S |
| β-谷甾醇 | β-Sitosterol | 83-46-5 | 414.71 | Saukewa: C29H50O |
| 菜油甾醇 | Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | Oleanolic acid | 508-02-1 | 456.7 | Saukewa: C30H48O3 |
| BAYANIN KAYAN SAURARA | ||
| Sunan samfur: | Vinca rosea asalin | |
| Sunan Botanical: | Catharanthus roseus (L.) | |
| Bangaren shuka | Fure | |
| Ƙasar Asalin: | China | |
| KAYAN NAZARI | BAYANI | HANYAR GWADA |
| Bayyanar | Kyakkyawan foda | Organoleptic |
| Launi | Brown lafiya foda | Na gani |
| Wari & Dandanna | Halaye | Organoleptic |
| Ganewa | Daidai da samfurin RS | HPTLC |
| Cire Rabo | 4:1-20:1 | |
| Binciken Sieve | 100% ta hanyar 80 mesh | USP39 <786> |
| Asarar bushewa | ≤ 5.0% | Yuro.Ph.9.0 [2.5.12] |
| Jimlar Ash | ≤ 5.0% | Yuro.Ph.9.0 [2.4.16] |
| Jagora (Pb) | ≤ 3.0 mg/kg | Eur.Ph.9.0 <2.2.58>ICP-MS |
| Arsenic (AS) | ≤ 1.0 mg/kg | Eur.Ph.9.0 <2.2.58>ICP-MS |
| Cadmium (Cd) | ≤ 1.0 mg/kg | Eur.Ph.9.0 <2.2.58>ICP-MS |
| Mercury (Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | Eur.Ph.9.0 <2.2.58>ICP-MS |
| Karfe mai nauyi | ≤ 10.0 mg/kg | Yuro.Ph.9.0 <2.4.8> |
| Ragowar Magani | Daidaita Eur.ph. 9.0 <5,4> da EC Dokar Turai 2009/32 | Yuro.Ph.9.0 <2.4.24> |
| Ragowar magungunan kashe qwari | Bi Dokokin (EC) No.396/2005 gami da annexes da sabuntawa masu zuwa Reg.2008/839/CE | Gas Chromatography |
| Kwayoyin Aerobic (TAMC) | ≤10000 cfu/g | USP39 <61> |
| Yisti/Moulds (TAMC) | ≤1000 cfu/g | USP39 <61> |
| Escherichia coli: | Babu a cikin 1g | USP39 <62> |
| Salmonella spp: | Babu a cikin 25g | USP39 <62> |
| Staphylococcus aureus: | Babu a cikin 1g | |
| Listeria monocytogenes | Babu a cikin 25g | |
| Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
Catharanthus roseus Cire Foda, ko Vinca rosea tsantsa, wanda aka samo daga tsiron periwinkle na Madagascar, yana da halaye da yawa:
Haɗaɗɗen Halittu:Fitar da foda ya ƙunshi mahadi masu rai irin su vinblastine da vincristine, waɗanda aka sani don abubuwan da za su iya amfani da su na magani, musamman a fagen maganin ciwon daji.
Abubuwan Magunguna:Ana ƙididdige foda mai tsantsa don yuwuwar amfanin magani, gami da maganin ciwon daji, maganin ciwon sukari, da kaddarorin hauhawar jini, da sauransu.
Asalin Halitta:An samo shi daga shukar Catharanthus roseus, wanda aka sani da yanayin yanayinsa da kuma amfani da magungunan gargajiya.
Aikace-aikacen Magunguna:Ana cire foda ya dace don amfani da shi a cikin magungunan magunguna da bincike saboda yanayin da yake da shi da kuma yiwuwar aikace-aikacen warkewa.
inganci da Tsafta:An ƙera samfurin zuwa ma'auni masu inganci, yana tabbatar da tsafta, ƙarfi, da daidaito a cikin abun cikin sa na bioactive.
Sha'awar Bincike:Yana da sha'awar masu bincike da ƙwararrun kiwon lafiya saboda yuwuwar sa wajen haɓaka sabbin samfuran magunguna da jiyya.
Anan akwai fa'idodin kiwon lafiya na Catharanthus roseus Extract Powder a cikin gajerun jimloli:
1. Abubuwan da za su iya hana ciwon daji da aka danganta da kasancewar vinblastine da vincristine alkaloids.
2. Bincike ya nuna tasirin maganin ciwon sukari, mai yuwuwar taimakawa wajen sarrafa sukarin jini.
3. Yiwuwar amfani a cikin kula da hauhawar jini saboda abubuwan da aka ruwaito ta hypotensive.
4. An bincika don maganin rigakafi da maganin rigakafi don tallafawa lafiyar rigakafi.
5. Bincike sha'awar a cikin neuroprotective Properties don fahimi goyon bayan kiwon lafiya.
6. Yiwuwar aikace-aikacen a cikin ƙirar fata saboda abubuwan da aka ruwaito ta antioxidant Properties.
7. Ya yi karatu don tasirinsa na anti-inflammatory, wanda zai iya yin tasiri ga yanayin kiwon lafiya daban-daban.
8. An bincika don yuwuwar sa don tallafawa lafiyar gaba ɗaya da kuzari.
1. Maganin rigakafin ciwon daji da bincike saboda kasancewar vinblastine da vincristine alkaloids.
2. Haɓaka magungunan rigakafin ciwon sukari da ƙari.
3. Yiwuwar amfani a cikin kula da hauhawar jini da magunguna masu alaƙa.
4. Bincike a cikin novel therapeutic agents don yanayi daban-daban na likita.
5. Sinadarin maganin gargajiya da na ganye.
6. Bincika kayan sa don kula da fata da kayan kwalliya.
7. Binciken yuwuwar sa wajen magance cututtukan ƙwayoyin cuta.
8. Haɓaka kayan abinci na abinci don tallafawa lafiyar lafiya da lafiya gabaɗaya.
9. Bincike a cikin fa'idodin kiwon lafiya na neuroprotective da fahimi.
10. Yiwuwar aikace-aikace a cikin magungunan dabbobi da samfuran lafiyar dabbobi.
Waɗannan aikace-aikacen suna ba da haske game da yuwuwar amfani da Catharanthus roseus Extract Foda a cikin magunguna, kiwon lafiya, lafiya, da sassan bincike.
Catharanthus roseus Cire Foda, kamar samfuran halitta da yawa, na iya samun tasirin sakamako masu illa, musamman idan aka yi amfani da su a cikin nau'ikan da aka tattara. Wasu illolin da zasu iya haɗawa da:
Raunin Gastrointestinal:Kamar tashin zuciya, amai, ko gudawa a wasu mutane.
Hypotension:Saboda kaddarorin da aka bayar na hypotensive, yawan amfani da shi na iya haifar da ƙarancin hawan jini.
Tasirin Jijiya:Yawan allurai na iya haifar da alamun cututtukan jijiya kamar dizziness ko rudani.
Maganin Allergic:Wasu mutane na iya fuskantar rashin lafiyar jiki, musamman idan sun san ciwon daji.
Ma'amalar Magunguna:Yana iya yin hulɗa tare da wasu magunguna, don haka ana ba da shawarar yin hankali, musamman ga mutane akan wasu magunguna.
Yana da mahimmanci a tuntuɓi mai sana'a na kiwon lafiya kafin amfani da Catharanthus roseus Extract Foda, musamman ma idan kuna da yanayin rashin lafiya ko kuma kuna shan magunguna. Wannan zai taimaka tabbatar da aminci da dacewa da amfani.
Marufi Da Sabis
Marufi
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