Corydalis Cire Tetrahydropalmatine (dl-THP)
Tetrahydropalmatine (THP), wanda kuma aka sani da dl-THP, Corydalin hydrochloride, ko Corydalin Tube Extract, wani fili ne wanda aka rarraba shi azaman alkaloid isoquinoline. Ana fitar da shi daga tuber na ganyen Corydalis yanhusuo na kasar Sin. THP wani abu ne mara launi ko kodadde rawaya crystalline tare da ɗanɗano ɗanɗano mai ɗaci da wurin narkewa na 147-149 ° C. A zahiri baya narkewa cikin ruwa amma yana narkewa sosai a cikin ether, chloroform, da ethanol. Hydrochloride da gishiri sulfate suna narkewa cikin ruwa.
An yi nazarin THP don tasirin magunguna daban-daban, ciki har da analgesic, anesthetic, neuroprotective, antiplatelet aggregation, antiulcer, antitumor, da anti-jaraba Properties. An yi imanin yin amfani da tasirin analgesic ta hanyar daidaita ayyukan mai karɓar dopamine na tsakiya kuma ya nuna yuwuwar kare ƙwayoyin cuta daga raunin ischemic. Bugu da ƙari, THP ya nuna tasirin tasirin antiplatelet kuma an bincika shi don yuwuwar sa wajen magance ulcers, hana haɓakar ƙwayar ƙwayar cuta, da kuma taimakawa cikin jarabar ƙwayoyi.
Gabaɗaya, Tetrahydropalmatine (dl-THP) wani fili ne tare da kaddarorin magunguna daban-daban kuma ya kasance batun babban bincike don yuwuwar aikace-aikacen warkewa. Don ƙarin bayani tuntuɓigrace@biowaycn.com.
Anan ga samfuran samfuran Tetrahydropalmatine (THP) tare da fa'idodin lafiyar su:
1. Abubuwan Ciwon Jiyya:THP yana nuna tasirin analgesic ta hanyar daidaita ayyukan mai karɓar dopamine na tsakiya, yana ba da jin daɗin jin zafi ba tare da yuwuwar jaraba ba.
2. Tasirin Neuroprotective:THP ya nuna yuwuwar kare ƙwayoyin cuta daga raunin ischemic, rage apoptosis neuronal, da rage matakan glutamate a cikin kwakwalwa, wanda zai iya ba da gudummawa ga kaddarorin neuroprotective.
3. Haɗin Antiplatelet:An gano THP don hana haɓakar platelet, mai yuwuwar rage haɗarin samuwar jini da abubuwan da ke da alaƙa da cututtukan zuciya.
4. Tallafin Lafiyar Ciki:THP ya nuna tasirin anti-ulcer kuma yana iya taimakawa wajen rage ƙwayar acid na ciki, yana ba da taimako daga cututtuka na ciki da kuma yanayi masu dangantaka.
5. Ayyukan Antitumor mai yuwuwar:THP ya nuna tasirin cytotoxic akan ƙwayoyin ƙwayar cuta, yana ba da shawara mai yuwuwar rawar hana haɓakar ƙwayar cuta.
6. Kayayyakin Anti-Addiction:An yi nazarin THP don yuwuwar sa don rage alamun janyewar da ke da alaƙa da opioid da jaraba mai motsa rai, yana ba da alƙawarin a cikin jiyya na jaraba da sake dawowa.
Waɗannan fasalulluka suna nuna fa'idodin kiwon lafiya iri-iri da yuwuwar aikace-aikacen warkewa na Tetrahydropalmatine (THP).
Tetrahydropydalin (dl-THP) na cikin alkaloids na isoquinoline kuma alkaloids ne, galibi a cikin halittar Corydalis lucidum (Yan Hu Suo), amma kuma a cikin wasu tsire-tsire irin su Stephania rotunda. Wadannan tsire-tsire suna da amfani na gargajiya a cikin maganin gargajiya na kasar Sin.Corydalis shine tsire-tsire na herbaceous na shekara-shekara, tsayin 10 zuwa 20 cm, tare da tubers masu siffar zobe. Tushensa na sama-kasa gajere ne kuma siriri, tare da ma'auni sama da tushe. Ganyen basal da ganyen cauline suna kama da siffa, tare da tsumma; Ganyen cauline suna canzawa, tare da ganye 2 da 3 fili. Ganye na biyu sau da yawa yakan rabu bai cika ba kuma yana da zurfi sosai. Ƙananan ganye suna da tsayi, m, ko m. Linear, tsayin kusan cm 2, tare da koli mai kaifi ko kaifi da kyawawan gefuna. Inflorescencensa yana da nau'in tsereme, tare da m ganye ko sabanin ganye; bracts suna da fadi da lanceolate; furannin suna da ja-ja-ja-ja-ja-ja-ja-ja kuma suna girma a kwance a kan ƙwanƙwasa siriri, waɗanda tsayinsu ya kai 6 mm; calyx yana faɗuwa da wuri; Furen suna 4 kuma na waje na waje 2 Yankunan sun ɗan fi girma, tare da gefuna ruwan hoda da tsakiyar shuɗi-purple. Akwai kashi ɗaya na sama, kuma wutsiya tana faɗaɗa zuwa tsayi mai tsayi. Tsawon spur ya kai kusan rabin jimlar tsayin. Yankuna 2 na ciki sun fi na waje kunkuntar. Ƙarshen saman yana da shuɗi-purple kuma ya warke, kuma ƙananan ɓangaren ruwan hoda ne; Stamen ɗin su 6 ne, kuma an haɗa filament ɗin zuwa ɗaure biyu, kowannensu yana da anthers 3; Ovary yana da lebur-cylindrical, salon gajere ne kuma sirara, kuma stigma shine 2, kamar ƙaramin malam buɗe ido. 'Ya'yan itacensa capsule ne. Ana samar da Corydalis a cikin tsaunuka ko ciyayi. Manyan wuraren da ake nomawa sun hada da Zhejiang, Hebei, Shandong, Jiangsu, da sauran wurare.
| Bincike | Ƙayyadaddun bayanai |
| Assay | Tetrahydropalmatine ≥98% |
| Bayyanar | Foda mai haske zuwa fari Foda |
| Ash | ≤0.5% |
| Danshi | ≤5.0% |
| Maganin kashe qwari | Korau |
| Karfe masu nauyi | ≤10pm |
| Pb | ≤2.0pm |
| As | ≤2.0pm |
| wari | Halaye |
| Girman barbashi | 100% ta hanyar 80 raga |
| Microbiological: | |
| Jimlar kwayoyin cuta | ≤1000cfu/g |
| Fungi | ≤100cfu/g |
| Salmgosella | Korau |
| Coli | Korau |
Anan ga masana'antun aikace-aikacen samfur na Tetrahydropalmatine (THP):
1. Magunguna:Ana amfani da THP a cikin masana'antar harhada magunguna don haɓaka magungunan kula da jin zafi da magungunan neuroprotective.
2. Abubuwan gina jiki:Ana amfani da THP a cikin masana'antar abinci mai gina jiki don samar da ƙarin abubuwan da ke niyya don rage jin zafi da tallafin lafiyar ciki.
3. Biotechnology:THP ta sami aikace-aikace a cikin fasahar kere-kere don bincike kan hanyoyin kwantar da hankali na antiplatelet da yuwuwar maganin cutar kansa.
4. Lafiya:An haɗa THP cikin samfuran kiwon lafiya don sarrafa jaraba da alamun cirewa da ke da alaƙa da opioid da amfani mai kuzari.
5. Kayan shafawa:Ana bincika THP a cikin kayan kwalliya don yuwuwar lafiyar fata da aikace-aikacen rigakafin kumburi.
Waɗannan masana'antu suna nuna nau'ikan yuwuwar aikace-aikacen Tetrahydropalmatine (THP) a cikin haɓaka samfura daban-daban da mahallin bincike.
Ana kera samfuran mu ta amfani da tsauraran matakan sarrafa inganci kuma suna manne da madaidaitan matakan samarwa. Muna ba da fifiko ga aminci da ingancin samfuranmu, muna tabbatar da cewa ya cika ka'idoji da takaddun shaida na masana'antu. Wannan sadaukarwa ga inganci yana nufin kafa amana da dogaro ga amincin samfuranmu. Tsarin samarwa gabaɗaya shine kamar haka:
Ajiya:Ajiye a wuri mai sanyi, bushe, da tsabta, Kariya daga danshi da haske kai tsaye.
Kunshin Girma:20~25kg/drum.
Lokacin Jagora:Kwanaki 7 bayan odar ku.
Rayuwar Shelf:shekaru 2.
Bayani:Ana iya samun takamaiman ƙayyadaddun bayanai.
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A karkashin 100kg, 3-5days
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